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At a median follow-up of 3.2 years, vaccine-induced neoantigen-specific CD 8 T cell responses are Substantially associated with extended RFS, with responders exhibiting a median RFS that has not been achieved, compared to 13.4 months in non-responders

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Species within Lactobacillus and Bifidobacterium contribute to efficient uptake and utilization of trace minerals, including calcium, phosphorus, and magnesium, therefore boosting the production of calcium-binding proteins and enhancing bone mineralization (208)

However, it is widely agreed that the extent of surgical resection is an important prognostic factor while no definitive data is available on the benefit of postoperative radiotherapy[2]